The philosophy of mathematics plays a vital role in the mature philosophy of Charles S. Peirce. Peirce received rigorous mathematical training from his father and his philosophy carries on in decidedly mathematical and symbolic veins. For Peirce, maths was a philosophical tool and many of his most productive ideas rest firmly on the foundation of mathematical principles. This volume collects Peirce's most important writings on the subject, many appearing in print for the first time. Peirce's determination to understand matter, the cosmos, and "the grand design" of the universe remain relevant for contemporary students of science, technology, and symbolic logic.