Seconds before the Earth is demolished to make way for a galactic freeway, Arthur Dent is plucked off the planet by his friend Ford Prefect, a researcher for the revised edition of The Hitch Hiker's Guide to the Galaxy who, for the last fifteen years, has been posing as an out of work actor. Together this dynamic pair begin their journey through space aided by quotes from The Hitch Hiker's Guide "A towel is about the most massively useful thing an interstellar hitchhiker can have" and a galaxy-full of fellow travellers: Zaphod Beeblebroxthe two-headed, three-armed ex-hippie and totally out to lunch president of the galaxy; Trillian, Zaphod's girlfriend (formally Tricia McMillan), whom Arthur tried to pick up at a cocktail party once upon a time zone; Marvin, a paranoid, brilliant and chronically depressed robot;and Veet Voojagig, a former graduate student who is obsessed with the disappearance of all the ball-point pens he has bought over the years.

道格拉斯·亚当斯（1952—2001），英国作家，毕业于剑桥大学。主要作品就是银河系漫游五部曲。包括《银河系漫游指南》、《宇宙尽头餐馆》、《生命、宇宙及一切》、《再见，谢谢鱼》和《基本无害》。这个系列被西方科幻读者奉为“科幻圣经”之一。由于银河系漫游系列小说的突出成就，国际小行星管理委员会甚至还将一颗小行星命名为阿瑟·邓特——该系列的主人公。

2001年，亚当斯因心脏病猝发离世——此前正在与好莱坞制片商合作，共同将《银河系漫游指南》搬上银幕。2005年4月29日，由迪斯尼公司拍摄的《银河系漫游指南》正式公映。首映周便获得二千一百七十多万美元，成为当周北美票房冠军。